IL-4 anticorps

N° du produit ABIN6964013

Cet anticorps Rat Monoclonal détecte spécifiquement IL-4 dans Neut. Il présente une réactivité envers Souris et a été mentionné dans 3+ publications.

Aperçu rapide pour IL-4 anticorps (ABIN6964013)

Antigène: IL-4 (IL4) (Interleukin 4 (IL4))

Reactivité: Souris

Hôte: Rat

Clonalité: Monoclonal

Conjugué: Cet anticorp IL-4 est non-conjugé

Application: Neutralization (Neut)

Clone: 11B11

Détail du produit anti-IL-4 anticorps

Specificité: Native and recombinant mouse IL-4

Purification: Purified from in vitro cultures by protein G affinity chromatography.

Immunogène: Recombinant mouse IL-4

Isotype: IgG1

Information d'application

Indications d'application: Neutralization of mouse IL-4 bioactivity. It is recommended to establish the optimal antibody concentration for the assay system used. The antibody is also suitable for immunoassays.

Restrictions: For Research Use only

Stockage

Concentration: 1 mg/mL

Buffer: supplied at 1 mg/mL in PBS free of preservatives

Agent conservateur: Without preservative

Stock: 4 °C,-20 °C

Stockage commentaire: Store product at 4-8°C or frozen at -20°C or below. Avoid repeated freezing/ thawing.

Date de péremption: 18 months

Références pour anticorps anti-IL-4 (ABIN6964013)

Cavassani, Tristao, Oliveira, Rocha, Vancim, Moreira, Campanelli, Panagio, Milanezi, Martinez, Rossi, Silva: "Cell-free antigens from Paracoccidioides brasiliensis drive IL-4 production and increase the severity of paracoccidioidomycosis." dans: PLoS ONE, Vol. 6, Issue 6, pp. e21423, (2011) (PubMed).

Costa, Carregaro, Lima-Júnior, Silva, Milanezi, Cardoso, Giudice, de Jesus, Carvalho, Almeida, Silva: "BALB/c mice infected with antimony treatment refractory isolate of Leishmania braziliensis present severe lesions due to IL-4 production." dans: PLoS neglected tropical diseases, Vol. 5, Issue 3, pp. e965, (2011) (PubMed).

Iizuka, Ikarashi, Yoshida, Heike, Takeda, Quinn, Wakasugi, Kitagawa, Takaue: "Interleukin (IL)-4 promotes T helper type 2-biased natural killer T (NKT) cell expansion, which is regulated by NKT cell-derived interferon-gamma and IL-4." dans: Immunology, Vol. 123, Issue 1, pp. 100-7, (2008) (PubMed).

Détails sur IL-4

Antigène: IL-4 (IL4) (Interleukin 4 (IL4))

Autre désignation: IL4

ID gène: 16189

Pathways: Signalistation JAK/STAT, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Proton Transport, Activated T Cell Proliferation